Protein Info for SMc01956 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 transmembrane" amino acids 417 to 437 (21 residues), see Phobius details PF00903: Glyoxalase" amino acids 4 to 124 (121 residues), 25.5 bits, see alignment E=7.3e-10

Best Hits

KEGG orthology group: K06999, (no description) (inferred from 100% identity to smk:Sinme_2539)

Predicted SEED Role

"Glyoxalase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92K03 at UniProt or InterPro

Protein Sequence (518 amino acids)

>SMc01956 hypothetical protein (Sinorhizobium meliloti 1021)
MTSGIHHITLIARKVQANVDFYVGFLGLHLVKRTGGYEDPNQLHLFYGDAAGSPGSLVSF
LVWEDGSPGRVGYGQPSEIAFAIPPESIGYWMTRALKFNIQATGPSQEFGEPVLRLKDPD
GVIVKLVGTNALAEPAPWAGRDIPETDSIRRLRGATVLTEKPKDTAHFLQNHFGYTETGA
TESIRRLTSSSGDVIDVRDAGGFWSAAPGTGTIDHIAFRAPDEATVLAVRADLEQEHAGA
TNAHDRKYFFSLYVREPGGALCELATDGPGFTVDEAPDALGTTLFLPPHLASDPTATLVR
LPQFALPGEPRVPQRDLPFIHRFHRPEKANDRTFVLLHGSGGNEIDMLPFGHQLDPHATL
LGVRGRSAEEGFPRWFRRFSMTKFDQQDIRSEAEAFAAFVEGARESYGLDPEKTVFIGYS
NGANLLAAVLLLHPGIVRNAVMMRAMAALESAPEPDLAGTRVLMLTGKDDPYGKHAPELK
TALRASGADFEEADLDTGHGIGVEDIAVIRPWLAESGI