Protein Info for SMc01950 in Sinorhizobium meliloti 1021

Annotation: high-affinity branched-chain amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 108 to 130 (23 residues), see Phobius details amino acids 136 to 160 (25 residues), see Phobius details amino acids 162 to 182 (21 residues), see Phobius details amino acids 184 to 184 (1 residues), see Phobius details amino acids 186 to 208 (23 residues), see Phobius details amino acids 215 to 234 (20 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 330 to 349 (20 residues), see Phobius details amino acids 365 to 392 (28 residues), see Phobius details amino acids 413 to 430 (18 residues), see Phobius details PF11862: DUF3382" amino acids 19 to 115 (97 residues), 65.5 bits, see alignment E=4.3e-22 PF02653: BPD_transp_2" amino acids 135 to 427 (293 residues), 161.3 bits, see alignment E=2.7e-51

Best Hits

KEGG orthology group: K01998, branched-chain amino acid transport system permease protein (inferred from 100% identity to sme:SMc01950)

Predicted SEED Role

"Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92MX2 at UniProt or InterPro

Protein Sequence (461 amino acids)

>SMc01950 high-affinity branched-chain amino acid ABC transporter permease (Sinorhizobium meliloti 1021)
MANVASTTASAGSELTARALREAVFAGLITLGMFVLFVGLKTDQNIRNELILTQRWGLLA
TFVAIAMVGRFLMVAYVQPRLAQRKAAKAAAPDVVKEETFFSRNWSKIAVILLLIYPPVI
VALVGVQGSLKWVDNFGIQILIYVMLAWGLNIVVGLAGLLDLGYVAFYAVGAYSYALLSS
YFGLSFWVLLPIAGLLAACWGVVLGFPVLRLRGDYLAIVTLAFGEIIRLVLINWTEVTKG
TFGVSGIAKATLFGIKFDATKDGFAAMMGLPMSSAYYKIFLFYLILGLALLTAFVTIRLR
RMPIGRAWEALREDEIACRSLGINTVTTKLTAFATGAMFGGFAGSFFAVRQGFVSPESFV
FLESAVILAIVVLGGMGSLTGIAIAAVVMIGGTEILRELTFLKMIFGPTFTPELYRMLIF
GLAMVVVMVWKPRGFVGSREPTAFLRERRAISGSFTKEGHG