Protein Info for SMc01942 in Sinorhizobium meliloti 1021

Annotation: urease accessory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 100% identical to URED_RHIME: Urease accessory protein UreD (ureD) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03190, urease accessory protein (inferred from 100% identity to sme:SMc01942)

Predicted SEED Role

"Urease accessory protein UreD" in subsystem Urea decomposition

MetaCyc Pathways

urea degradation II (1/1 steps found)
superpathway of allantoin degradation in plants (4/8 steps found)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P42888 at UniProt or InterPro

Protein Sequence (277 amino acids)

>SMc01942 urease accessory protein (Sinorhizobium meliloti 1021)
MEPAAIIAPQRARGEGRLVAKAEGGRTRIAELYQEGCAKIRLPKTFDASMEAVLINSSGG
VTGGDRLSWEFRAGKGTKLTLTTQACEKVYKAAAGTAEIATRISVAAGAHVDWLPQETIL
FDRSALSRSLEVDLAADASFLAVEAVLIGRKAMGEEVRAGLFRDNWRIRSGGRLIHAENL
ALAGDIAALASRRAVLDGAAAFATLVYAAPDCESQLSKLRLALAGHALSGVSHYDVGGRD
KIVARVAAADGFALRKILIPLISHLRKDASVPKVWTL