Protein Info for SMc01869 in Sinorhizobium meliloti 1021

Annotation: transport transmembrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 436 transmembrane" amino acids 27 to 57 (31 residues), see Phobius details amino acids 66 to 88 (23 residues), see Phobius details amino acids 99 to 119 (21 residues), see Phobius details amino acids 126 to 152 (27 residues), see Phobius details amino acids 164 to 187 (24 residues), see Phobius details amino acids 199 to 220 (22 residues), see Phobius details amino acids 253 to 277 (25 residues), see Phobius details amino acids 289 to 310 (22 residues), see Phobius details amino acids 318 to 338 (21 residues), see Phobius details amino acids 345 to 369 (25 residues), see Phobius details amino acids 381 to 399 (19 residues), see Phobius details amino acids 411 to 429 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 27 to 237 (211 residues), 88.1 bits, see alignment E=6.3e-29 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 33 to 423 (391 residues), 458.7 bits, see alignment E=9.1e-142 PF07690: MFS_1" amino acids 33 to 386 (354 residues), 83.3 bits, see alignment E=1.7e-27 amino acids 281 to 429 (149 residues), 40.9 bits, see alignment E=1.3e-14

Best Hits

Swiss-Prot: 61% identical to YHJE_ECOLI: Inner membrane metabolite transport protein YhjE (yhjE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_2153)

Predicted SEED Role

"Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92NM2 at UniProt or InterPro

Protein Sequence (436 amino acids)

>SMc01869 transport transmembrane protein (Sinorhizobium meliloti 1021)
MTDATTSLSPQDGALHRQAVNSPARVLFASLVGTTIEFFDFYVYATAAVIIFPHLFFPAA
DPTSAMLQSLATFSIAFFARPLGAVIFGHFGDRIGRKATLVAALMTMGISTVVIGLLPTY
STIGVVAPLLLALCRFGQGLGLGGEWGGAVLLATENAPEGKRSWYAMFPQLGAPIGFILS
AGTFLILGEVMSEEAFLAWGWRVPFIASVLLVIVGLYVRLKITETPEFQKAIDKHERVEV
PVAAIFRSHKRSLVLGTFVALATFVLFYLMTVFSLSWGTTKLGYSREQFLLVQMTGVVFF
GLMIPVSGILSDRFGRRLVLVLTTIGIGVFGLFMAPLLSSGLGGAFVFSIVGLGLMGLTY
GPIGAALAAPFPTAVRYTGASMTFNLAGIFGASLAPYIATWLATNYSLGHVGYYLLAAAS
ITLVCLLLSNEEEVSG