Protein Info for SMc01786 in Sinorhizobium meliloti 1021

Annotation: integration host factor subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 112 TIGR00987: integration host factor, alpha subunit" amino acids 5 to 96 (92 residues), 138 bits, see alignment E=5.6e-45 PF00216: Bac_DNA_binding" amino acids 7 to 94 (88 residues), 91.8 bits, see alignment E=1.3e-30

Best Hits

Swiss-Prot: 100% identical to IHFA_RHIME: Integration host factor subunit alpha (ihfA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K04764, integration host factor subunit alpha (inferred from 100% identity to sme:SMc01786)

Predicted SEED Role

"Integration host factor alpha subunit" in subsystem DNA structural proteins, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92QT3 at UniProt or InterPro

Protein Sequence (112 amino acids)

>SMc01786 integration host factor subunit alpha (Sinorhizobium meliloti 1021)
MSGKTVTRADLAESVFRKVGLSRTESAELVETVIDEICNAIVRGESVKLSSFATFQVRDK
NERIGRNPKTGEEVPISPRRVMTFKASNVLKQRVLKAHLSRKSKLKPSNPAG