Protein Info for SMc01721 in Sinorhizobium meliloti 1021

Annotation: inner membrane protein translocase component YidC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 595 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 366 to 393 (28 residues), see Phobius details amino acids 438 to 461 (24 residues), see Phobius details amino acids 499 to 518 (20 residues), see Phobius details amino acids 530 to 557 (28 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 5 to 372 (368 residues), 342.1 bits, see alignment E=5.6e-106 PF14849: YidC_periplas" amino acids 83 to 362 (280 residues), 272.3 bits, see alignment E=7.5e-85 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 373 to 571 (199 residues), 232.4 bits, see alignment E=4.6e-73 PF02096: 60KD_IMP" amino acids 374 to 571 (198 residues), 215 bits, see alignment E=6.3e-68

Best Hits

Swiss-Prot: 100% identical to YIDC_RHIME: Membrane protein insertase YidC (yidC) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 100% identity to sme:SMc01721)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92SF5 at UniProt or InterPro

Protein Sequence (595 amino acids)

>SMc01721 inner membrane protein translocase component YidC (Sinorhizobium meliloti 1021)
MMENNRNYFVAIALSVLILIAWQFFYVSPKMEKDRIAAEQAQQAQQTQQQPGAQPAAPGQ
ALPGGAIPSAGESRDQAIGKSARVAIDTPALSGSINLTGARFDDLKLKGYRETVDPKSPV
ITLFSPAETADGYFTEIGYIGSDATGSVPGPQTTWTLSGGDKLTPSTPVTLSYTNDKGIT
FARTISVDDRYMFQVVDSIKNETAAPVSLSSYGRVTRFNKPTTPSIYVLHEGFVGVAGEH
GLQEVGYSKVEDDEPVEPGKSTGGWLGITDKYWAATIVPPQATPFDIRFSHFADGRPRYQ
SDYKSDAVTVAPGQSVELKNLVFAGAKEVPVVDNYEVAYSIPNFDKLIDWGWFYFITKPM
FKMMDFFFRLFGNFGIAILITTIVVKLIFFPLANKQYASMANMKKVQPKMEELKKKFGDD
RMGLQQAMMQLYKEEKINPLAGCWPILIQIPVFFALYKVIYVTIEMRHAPFFGWIQDLSA
PDPTTIINLFGLLPFEGPAFLHLGIWPIIMGVTMFLQMRMNPTPPDPTQAMLFTWMPVVF
TFMLASFPAGLVIYWAWNNTLSILQQGIIMKRQGVKVELFDNLKSLFSKKPKPAE