Protein Info for SMc01720 in Sinorhizobium meliloti 1021

Annotation: ribonuclease P

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 128 PF00825: Ribonuclease_P" amino acids 12 to 110 (99 residues), 78 bits, see alignment E=2.8e-26 TIGR00188: ribonuclease P protein component" amino acids 12 to 109 (98 residues), 56.3 bits, see alignment E=1.7e-19

Best Hits

Swiss-Prot: 100% identical to RNPA_RHIME: Ribonuclease P protein component (rnpA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03536, ribonuclease P protein component [EC: 3.1.26.5] (inferred from 100% identity to smk:Sinme_0078)

Predicted SEED Role

"Ribonuclease P protein component (EC 3.1.26.5)" in subsystem tRNA processing (EC 3.1.26.5)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92SF4 at UniProt or InterPro

Protein Sequence (128 amino acids)

>SMc01720 ribonuclease P (Sinorhizobium meliloti 1021)
MTTDKDKMAVGRLKSRPQFLAVRAGESRRGPLFLLEVLDRNDPEGEARVGFTVTKKHGNA
VERNRMRRRLKEAVRLSAGFAMKPGHDYVIVARRDLLNAPFDALTRALRDRIENKPKQKR
PPAGSRKS