Protein Info for SMc01576 in Sinorhizobium meliloti 1021
Annotation: oxidoreductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to smk:Sinme_2189)MetaCyc: 41% identical to pipecolate oxidase (Pseudomonas putida)
L-pipecolate oxidase. [EC: 1.5.3.7]
Predicted SEED Role
"FAD dependent oxidoreductase"
MetaCyc Pathways
- L-lysine degradation V (5/9 steps found)
- L-lysine degradation II (L-pipecolate pathway) (4/9 steps found)
- superpathway of L-lysine degradation (15/43 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.5.3.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q92NJ3 at UniProt or InterPro
Protein Sequence (429 amino acids)
>SMc01576 oxidoreductase (Sinorhizobium meliloti 1021) MATERALPNLWHATAPAAPRTAPLAGDLTVEVAIVGGGFTGLSAALHLAETGIRTAVIEA RMIGFGGSGRNVGLVNAGMWVQPDDLIATLGAAAGNRLLDELGDGPSFVYDLVAKHGIEC EAVRNGTLHMSVGAEGLKEIREREAQWKKRGAPVEVLSAEKAHALSGAEGFTGALLDRRA GTIQPLAYARGLARAALAAGAEIFTDTPLLAASRQGDLWNLKTPRGTVTARHVILATNAY GSLVTGVPWKEYRQELTILPYFQFATNPLPDNVAARILPERQGAWDTGLVMTSFRMDRQN RLIFGSIGRLDAIAAGTHRAFAARSVRKLFPYIGDFRFEHWWDGRIGMTTNNLPAMHVLA PNVVSISGYNGRGIAPGTVFGRALARHVTGDTSAIPLAETPVTPDPWRTLKSAFYHAGAQ AKHFIDKRF