Protein Info for SMc01525 in Sinorhizobium meliloti 1021

Annotation: dipeptide binding periplasmic protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 546 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF00496: SBP_bac_5" amino acids 80 to 457 (378 residues), 310.1 bits, see alignment E=1.2e-96

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 100% identity to sme:SMc01525)

Predicted SEED Role

"Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) or Bacterial Chemotaxis (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92N26 at UniProt or InterPro

Protein Sequence (546 amino acids)

>SMc01525 dipeptide binding periplasmic protein (Sinorhizobium meliloti 1021)
MMHKLNGRFRVLAASAALAMAMGAAQPAFAETPKDTLVEGFAFDDIITMDPGEAFELSTA
EMTSNTYSLLVRLDLNDTSKVVGDLAESWTVSDDGLTYTFKLKSGMKFASGNPITAEDVA
YSFERAVKLDKSPAFILTQFGLTGDNVTEKAKAADAETFVFTVDQPYAPSFVLNCLTATV
ASVVDKKLVLEHVKSVTPSDEYKYDNDFGNEWLKTGYAGSGPFKLREWRANEVVVLERNE
NFYGEPAKLARVIYRHMKESSGQRLALEAGDIDVARNLEPGDYEAVGKNADLATASAPKG
TVYYISLNQKNETLAKPEVQQAFKYLVDYDAIGATLIKGIGEIHQSFLPKGVLGALNENP
YTFDVAKAKELLAKAGYPDGFTVTMDVRNTQPVTGVAESFQQTLAQAGVKLEIIPGDGKQ
TLTKYRARNHDMYIGQWGMDYFDPHSNADTFTNNPDNSDEGTNKTLAWRNAWDVPELSKK
TKDALLERDSAKRADIYKELQKTVLENSPFVFIFQQTEVAGLRGNLQGFKLGPSFDTNYV
WNVSKE