Protein Info for SMc01047 in Sinorhizobium meliloti 1021
Annotation: D-amino acid aminotransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 40% identical to DAAA_BACLI: D-alanine aminotransferase (dat) from Bacillus licheniformis
KEGG orthology group: K00824, D-alanine transaminase [EC: 2.6.1.21] (inferred from 100% identity to smk:Sinme_1264)Predicted SEED Role
"D-alanine aminotransferase (EC 2.6.1.21)" in subsystem Pyruvate Alanine Serine Interconversions (EC 2.6.1.21)
MetaCyc Pathways
- D-alanine degradation (1/1 steps found)
KEGG Metabolic Maps
- Arginine and proline metabolism
- D-Alanine metabolism
- D-Arginine and D-ornithine metabolism
- Lysine degradation
- Phenylalanine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.21
Use Curated BLAST to search for 2.6.1.21
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q92Q85 at UniProt or InterPro
Protein Sequence (287 amino acids)
>SMc01047 D-amino acid aminotransferase (Sinorhizobium meliloti 1021) MPRIAYVNGTYVRHAEAAIHVEDRGYQFADGVYEVCEVRHGFIIDLTRHLDRLGRSLGEL RIGWPMSRAALIHVIREVLRRNRVRNGLFYLQVTRGVARRDHVFPDADTPPSIVVTAKRT DPGAIARKNAEGISAITVPENRWDRVDIKSVGLLPNVLARQQAKEAGAQEAIFVDVDGMV KEGAATNVWIVDREGTLRTRPAESGILRGVTRTTLMDVAKPLGLAIEETAFSVEEMLAAR EVFITAATSICFPVVSVDGKTIGNGHPGSIAQNIRETFFDIAEKTVI