Protein Info for SMc01045 in Sinorhizobium meliloti 1021

Annotation: nitrogen regulation protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 PF00072: Response_reg" amino acids 5 to 114 (110 residues), 95.4 bits, see alignment E=7.2e-31 PF00158: Sigma54_activat" amino acids 142 to 305 (164 residues), 181 bits, see alignment E=4.9e-57 PF14532: Sigma54_activ_2" amino acids 143 to 310 (168 residues), 75.7 bits, see alignment E=1.3e-24 PF07728: AAA_5" amino acids 166 to 273 (108 residues), 26.6 bits, see alignment E=1.6e-09 PF02954: HTH_8" amino acids 412 to 450 (39 residues), 44.2 bits, see alignment 4e-15

Best Hits

Swiss-Prot: 67% identical to NTRX_AZOC5: Nitrogen assimilation regulatory protein NtrX (ntrX) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K13599, two-component system, NtrC family, nitrogen regulation response regulator NtrX (inferred from 100% identity to sme:SMc01045)

Predicted SEED Role

"Nitrogen regulation protein NtrX"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Q87 at UniProt or InterPro

Protein Sequence (454 amino acids)

>SMc01045 nitrogen regulation protein (Sinorhizobium meliloti 1021)
MAADILVVDDEEDIREIVSGILSDEGHETRTAFDSESALAAINDRVPRLIFLDIWMQGSK
LDGLALLDEIKNRHPDLPVVMISGHGNIETAVSAIKRGAYDFIEKPFKADRLILIAERAL
ENSKLKRENSELRRKSGDPVELIGTSVAVSQLRQMIEKVAPTNSRIMIQGPSGSGKELVA
RMIHRKSARANGPFVALNAAAITPDRMEIALFGTEGTTGQPRRTGALEEAHGGILYLDEV
GEMPRETQNKILRVLVDQQFERVGGSKRVKVDVRIISSTAYNLENMITEGLFREDLYHRL
AVIPVRVPALAERREDIPFLVDMFMRQVSEQAGIRPRKIGEDALAVLQAHDWPGNIRQLR
NNIERLMILARSDGPDTPITADMLPNEVGDTLPKISAQGDQHIMTLPLREAREMFERDYL
IAQINRFGGNISRTAEFVGMERSALHRKLKSLGV