Protein Info for SMc00857 in Sinorhizobium meliloti 1021

Annotation: protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 transmembrane" amino acids 93 to 109 (17 residues), see Phobius details amino acids 122 to 138 (17 residues), see Phobius details amino acids 255 to 273 (19 residues), see Phobius details PF01972: SDH_sah" amino acids 60 to 137 (78 residues), 25.2 bits, see alignment E=8.1e-10 PF01343: Peptidase_S49" amino acids 87 to 226 (140 residues), 103.7 bits, see alignment E=9.5e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_0556)

Predicted SEED Role

"macromolecule metabolism; macromolecule degradation; degradation of proteins, peptides, glycopeptides"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92RL7 at UniProt or InterPro

Protein Sequence (288 amino acids)

>SMc00857 protease (Sinorhizobium meliloti 1021)
MAGFFRKLMPKRFRRDGVTIPAIRLHGAIMAGGSPLRPVLNLATVAPLLEKAFSVKEAPA
VAISINSPGGSPVQSRLIYQRIRDLAQEKRKRVLIFVEDVAASGGYMIALAGDEIIADPT
SIVGSIGVVSGGFGFPDLLKKIGVERRVYTAGENKVVLDPFQPEKERDIEFLKGLQLEIH
DIFIQMVKSRRGSLLADHPDLFSGLFWTGQRGQELGLVDALGDIRGEVKKRYGEKARLEL
IQPARSLFGRRQPGAAVAGAITGPLVASAAAGLVEAVEERALWARFGL