Protein Info for SMc00536 in Sinorhizobium meliloti 1021

Annotation: transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 44 to 61 (18 residues), see Phobius details amino acids 73 to 91 (19 residues), see Phobius details amino acids 97 to 119 (23 residues), see Phobius details amino acids 131 to 154 (24 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 212 to 233 (22 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 279 to 297 (19 residues), see Phobius details amino acids 303 to 325 (23 residues), see Phobius details amino acids 335 to 357 (23 residues), see Phobius details amino acids 367 to 386 (20 residues), see Phobius details PF07690: MFS_1" amino acids 11 to 352 (342 residues), 141.2 bits, see alignment E=2.1e-45

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 100% identity to smk:Sinme_1688)

Predicted SEED Role

"MFS family multidrug efflux protein, similarity to bicyclomycin resistance protein Bcr"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92PH3 at UniProt or InterPro

Protein Sequence (409 amino acids)

>SMc00536 transporter (Sinorhizobium meliloti 1021)
MGLVEFIVTIAVMTASIALAIDSMLPALPSIGQTLDVANANDTQLVIGVFFLGFGLSQIF
FGSLSDAFGRRSVLLGGLALFSLSMFAASWVESIETLLLLRFIQGIGGAAVRITTMAIVR
DCFGGRDMARVMSYVMIVFMIVPIVAPTLGQVVIAYADWHWIFILIGVVGAALFVWALTR
MKESLPKEERLPLSVGAVLSGFRTVLTNRITCGYMIGMTLFTAVICAYVVSVQQVFGEVY
NLSDWMPIAFAGTAGGIAVANFANGYFVRSFGMRRISHAAMILFTLFAAIGYVLSLAGTP
AFAISYLLFSLLLMFFAVIATNFTAISLEPMGHLAGTATAVTGFVSTTGGALIGGAVGQL
FDGTLQPLFGGYALFGLLTILATLWAENGKLFTHPGDSDATHEHGGGHL