Protein Info for SMc00468 in Sinorhizobium meliloti 1021
Annotation: hypothetical protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K08296, phosphohistidine phosphatase [EC: 3.1.3.-] (inferred from 100% identity to smk:Sinme_1710)Predicted SEED Role
"Phosphohistidine phosphatase SixA"
KEGG Metabolic Maps
- Aminosugars metabolism
- Ascorbate and aldarate metabolism
- Ether lipid metabolism
- Fructose and mannose metabolism
- Lipopolysaccharide biosynthesis
- Nicotinate and nicotinamide metabolism
- Riboflavin metabolism
- Sphingolipid metabolism
- Thiamine metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.1.3.-
Use Curated BLAST to search for 3.1.3.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q92PF7 at UniProt or InterPro
Protein Sequence (178 amino acids)
>SMc00468 hypothetical protein (Sinorhizobium meliloti 1021) MQDSVVPAFQLLLLRHARSGWALPGQSDFDRALDDIGFAEAELTAQSAADHRIRPDLILC STAVRCRQTAEPLYRAFGEDIDIRYLDTLYTGPTTVYADLVEAHASRPSLMIIGHNPMME ELFRRILGEERAAAALADGYPPAGMAVIDFAARPKAGTAWTATLSKFLVPAPEEAEKG