Protein Info for SMc00357 in Sinorhizobium meliloti 1021

Annotation: elongation factor P

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 189 PF08207: EFP_N" amino acids 6 to 62 (57 residues), 57.7 bits, see alignment E=1.4e-19 TIGR00038: translation elongation factor P" amino acids 6 to 187 (182 residues), 210.6 bits, see alignment E=7.5e-67 PF01132: EFP" amino acids 70 to 123 (54 residues), 68.1 bits, see alignment E=7.7e-23 PF09285: Elong-fact-P_C" amino acids 131 to 186 (56 residues), 80 bits, see alignment E=1.2e-26

Best Hits

Swiss-Prot: 100% identical to EFP_RHIME: Elongation factor P (efp) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K02356, elongation factor P (inferred from 98% identity to smd:Smed_3478)

MetaCyc: 36% identical to protein chain elongation factor EF-P (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Translation elongation factor P" in subsystem Translation elongation factors eukaryotic and archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92ST6 at UniProt or InterPro

Protein Sequence (189 amino acids)

>SMc00357 elongation factor P (Sinorhizobium meliloti 1021)
MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRISDGVKVSERYRTTE
QVERAFVEDREHTFLYEDGEGFHFMNPETYDQLVMSSEDIGDLKAYLQEGMAVMLSIHEG
IAIAIDLPRHVTLEITETEPVVKGQTASSSYKPAVLSNGVRTLVPPHIQAGTRVVIATED
GSYVERAKD