Protein Info for SMa2393 in Sinorhizobium meliloti 1021

Annotation: RepB2 replication protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 TIGR03454: plasmid partitioning protein RepB" amino acids 2 to 325 (324 residues), 340 bits, see alignment E=1.6e-105 TIGR00180: ParB/RepB/Spo0J family partition protein" amino acids 60 to 227 (168 residues), 109.7 bits, see alignment E=1.5e-35 PF02195: ParBc" amino acids 63 to 154 (92 residues), 53.2 bits, see alignment E=2.7e-18 PF07506: RepB" amino acids 157 to 273 (117 residues), 43 bits, see alignment E=5.5e-15

Best Hits

KEGG orthology group: K03497, chromosome partitioning protein, ParB family (inferred from 100% identity to sme:SMa2393)

Predicted SEED Role

"Plasmid replication protein RepB" in subsystem Plasmid replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XG1 at UniProt or InterPro

Protein Sequence (333 amino acids)

>SMa2393 RepB2 replication protein (Sinorhizobium meliloti 1021)
MSRKDSKGLFANVLGQLENSAEKGGMQRSTSPHLLKVAAGVRQMQERSELAERLLKDGGQ
IVEIDPDEIMESAIRDRFDSGYSEAGIADLLESMREHGQSTPGLVRPVRGAARPFQIVFG
RRRLAAAKLLGIKFKAIARELSDEDAIVLQGEENSNRKDLSFIERCLFAQSQEAAGYRRD
VICKSLSTGRSHISEMIRIAAALPREILMQIGPAPEIGRRRWIEFEVRWAAHREPAKVAQ
LVLEQEQIQASSSDLRFTAVFEALTKVDVRAAASSTSDLISHGLVLGQIQRGKSAAKLTF
NKSVPSGFVDFIAGQIESLHDQFMQKQSSKQGD