Protein Info for SMa2209 in Sinorhizobium meliloti 1021

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF13531: SBP_bac_11" amino acids 33 to 281 (249 residues), 55.8 bits, see alignment E=1.2e-18 PF01547: SBP_bac_1" amino acids 35 to 278 (244 residues), 57.1 bits, see alignment E=6.2e-19 PF13416: SBP_bac_8" amino acids 42 to 299 (258 residues), 74.9 bits, see alignment E=1.9e-24 PF13343: SBP_bac_6" amino acids 89 to 295 (207 residues), 83 bits, see alignment E=4.9e-27

Best Hits

KEGG orthology group: K02055, putative spermidine/putrescine transport system substrate-binding protein (inferred from 100% identity to sme:SMa2209)

Predicted SEED Role

"Nucleoside ABC transporter, permease protein 1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XQ2 at UniProt or InterPro

Protein Sequence (340 amino acids)

>SMa2209 ABC transporter substrate-binding protein (Sinorhizobium meliloti 1021)
MYIRHLIAGAAISASWAGMAVAEDCALRVTTWGGSYQATYQAVAQKFEEEHNCRIEWVVG
ASPDHLIKARLGQVDVVTNTLLNSIAGEKEGLWQKLDPAKIPNMANLYPNAVHSPYTVFA
NVGDYVLAYNKDTVTTVPATWDELWKPEYKNRVVIYGIDHIPTLSLTVLQAEKNGGSIDN
VEPGLDRMAELIKSGNLIGSLDVESQMVSLFETGDAWLGMLATGRMKELLSKGVTNVSFV
RPEEGTFPLITSVNIHKDAKNPAMAAAFVNYILSSEVQVAFATRNLYAPTVKNAEIPDDF
EFRDLLVLNDAFGRLYLPDQEKITANKAGWQQQLNQKAMR