Protein Info for SMa2207 in Sinorhizobium meliloti 1021

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 PF00005: ABC_tran" amino acids 22 to 163 (142 residues), 124.6 bits, see alignment E=4.4e-40 PF08402: TOBE_2" amino acids 281 to 354 (74 residues), 58 bits, see alignment E=8.4e-20

Best Hits

Swiss-Prot: 46% identical to POTA_PSEF5: Spermidine/putrescine import ATP-binding protein PotA (potA) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 100% identity to sme:SMa2207)

MetaCyc: 45% identical to sn-glycerol 3-phosphate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-34-RXN [EC: 7.6.2.10]; 7.6.2.10 [EC: 7.6.2.10]

Predicted SEED Role

"putative ABC transporter, ATP-binding protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XQ3 at UniProt or InterPro

Protein Sequence (361 amino acids)

>SMa2207 ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MSNDSIQVEGITKRYGAMTAVDNVSFDVGQGEFVSLLGPSGCGKTTTLRMIAGFVDPSGG
LLRVRGRDVTHLPPEKRDLGFVFQNYALWPHMTVAENVAFGLKLRKKNRNFIRDKVAEAL
TTTGLSGYENRLPRQLSGGQQQRVALARALALEPQVLLMDEPLSNLDRALRVTMRRELKE
LQARMKMTTLYVTHDQEEALSMSNRVVIMNKGQVEQVAAPFELYENPATGFVADFVGITN
FLGGIVTSAEGGGVEVKLGSGQMLRAVTKQPVALGTKVRALIRPERVTLKTTAADGDNIL
TGQVVLAEYFGALLRYSVRLDSGDILRAEVHNFDSFIESGSRVWVCVSPEHLRLIPDERN
A