Protein Info for SMa2061 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 481 transmembrane" amino acids 393 to 410 (18 residues), see Phobius details PF06745: ATPase" amino acids 12 to 239 (228 residues), 142.6 bits, see alignment E=5.3e-45 amino acids 255 to 473 (219 residues), 103.2 bits, see alignment E=5.7e-33 PF13481: AAA_25" amino acids 267 to 408 (142 residues), 32.8 bits, see alignment E=2.2e-11

Best Hits

KEGG orthology group: K08482, circadian clock protein KaiC (inferred from 100% identity to sme:SMa2061)

Predicted SEED Role

"FIG01076388: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XW4 at UniProt or InterPro

Protein Sequence (481 amino acids)

>SMa2061 hypothetical protein (Sinorhizobium meliloti 1021)
MNVAERKKQTVVSSGISGLDEILRGGLPASNLYIVQGAPGSGKTTAALQFLRAGVALGEP
CIYVSLSQTRAELEAIALSHGWTLDGIRVEELSASDSINRAADQTIFQTTELRLDETRKA
IESAIEEHKPSRLVYDSLLEIRLITADSPRFRRELIAFKAFLAQRNIVALLLDTQTSETD
RTGEEVDGIAHGVIRLDKSLEEYGGVRRRIEVSKMRGVPVADGYHDMAIREGEGVVVFPR
IVPGAAARTVKPQLIKSGVDTLDEMFGGGQESGTTTLVIGQAGTGKSTMASLYATAALKR
GESVGLFLFEERIETFFRRSEGLGMALRQFHEDGQLILRDFNPNEISPGEFGQIVQQSVN
SEKVKVVVIDSFTGYLNSLPHREKAVRDIQSLLKYLARAGVLTILIVAQHGLLGQGVGID
VDVSFLGDTVLLLRIAEHEGRLRRSITVVKKRHGPHDLDVRELFIQSSGVSVIAYNPLPE
V