Protein Info for SMa1945 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 transmembrane" amino acids 30 to 54 (25 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 91 to 109 (19 residues), see Phobius details amino acids 116 to 140 (25 residues), see Phobius details amino acids 147 to 164 (18 residues), see Phobius details amino acids 170 to 192 (23 residues), see Phobius details PF00892: EamA" amino acids 33 to 163 (131 residues), 83.6 bits, see alignment E=7.8e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMa1945)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Y23 at UniProt or InterPro

Protein Sequence (286 amino acids)

>SMa1945 hypothetical protein (Sinorhizobium meliloti 1021)
MSARILCQQMFVWHTARMNKNAADIPMTPFLPALAIAGTVITWSFSFAAIGYALREVEPL
PLAAIRFALAAVFAIAWIAWRRPRWFLPRDFVVLAISGLLGIAAYNVLLNLGQAAVSAGA
AGFIVNTQPLFMVLLAVLFLKERFGRWNWVGTIVGFSGVALIASGQPGGLSFGTGSTLIV
LAAACAAAYSILQRPLFARAEPLDVTGARHRCRRSRPHALATGRRLPIDARASGHLADDH
VPGRRSGHYRSKLLDLRTQEFRCRAGRSISLFGSTVLCWTGVAPAR