Protein Info for SMa1650 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 102 to 126 (25 residues), see Phobius details amino acids 138 to 158 (21 residues), see Phobius details amino acids 176 to 195 (20 residues), see Phobius details amino acids 233 to 256 (24 residues), see Phobius details amino acids 276 to 301 (26 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 1 to 79 (79 residues), 36.8 bits, see alignment E=3.9e-13 PF00528: BPD_transp_1" amino acids 117 to 308 (192 residues), 93 bits, see alignment E=2e-30

Best Hits

Swiss-Prot: 34% identical to GSIC_SHIDS: Glutathione transport system permease protein GsiC (gsiC) from Shigella dysenteriae serotype 1 (strain Sd197)

KEGG orthology group: None (inferred from 99% identity to smk:Sinme_6093)

MetaCyc: 34% identical to glutathione ABC transporter membrane subunit GsiC (Escherichia coli K-12 substr. MG1655)
RXN0-11 [EC: 7.4.2.10]

Predicted SEED Role

"Nucleoside ABC transporter, permease protein 1"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YH8 at UniProt or InterPro

Protein Sequence (311 amino acids)

>SMa1650 ABC transporter permease (Sinorhizobium meliloti 1021)
MFHFTSKRLKHSLVLLFLASLVCFTLVVSAPGNVAVLIAELRGAVATPGYVEQVAEEIGL
NEPLLMRYVDWLGDAVRGNFGISYRTGQDVSADLAARMSVTGILIAGGAVIATLLSLALG
FLGALWPYRVPDRVSRGLALLGASTPTFFVGALMIYGFSVHFQLLPSFGFNGPQSWILPW
LTVSVLPAAVLSRVVRVGLEETMASPFVLTAKSKGLGRTAILFRDALPNITPIFINALGT
QVGLMTATAIIVEPLFAWQGLGDYFLAGVRFRDFMVVQACLLIFLTFFILVNLIVDLAVL
LTDPRIRRQWS