Protein Info for SMa1437 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 142 to 161 (20 residues), see Phobius details amino acids 173 to 174 (2 residues), see Phobius details amino acids 176 to 204 (29 residues), see Phobius details amino acids 225 to 252 (28 residues), see Phobius details amino acids 274 to 298 (25 residues), see Phobius details PF00528: BPD_transp_1" amino acids 112 to 303 (192 residues), 122 bits, see alignment E=1.2e-39

Best Hits

Swiss-Prot: 40% identical to OPPB_HAEIN: Oligopeptide transport system permease protein OppB (oppB) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 99% identity to smk:Sinme_5978)

MetaCyc: 37% identical to murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppB (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]; 7.4.2.6 [EC: 7.4.2.6]

Predicted SEED Role

"Probable ABC transporter permease"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92YS8 at UniProt or InterPro

Protein Sequence (304 amino acids)

>SMa1437 ABC transporter permease (Sinorhizobium meliloti 1021)
MLGYIGRRAYHSVISVIGLLTLVFFLTRLTGDPSALYLPLDSSLEARQAFARLNGLDQPI
YVQFFQYLQNLMSLDFGQSLRQNRSAIEVALEAFPATLKLALVAMSLATVLAIVVGALAA
ARPGSLFDRIAGLVSLAGASTPDFWIAIVGILVFAVGLGILPTSGTGTALHWIMPIVVLM
LRPFGLLVQVVRGTMISALASPFIKTAHAKGMKRRKIIFGHALRNSLLPVITVAGDLATG
LINGAVVVETIFGWPGIGKLMIDSIIQRDFAVVQSTILVTAIAIFIVNIAIDLLYAVLDP
RIRY