Protein Info for SMa1303 in Sinorhizobium meliloti 1021

Annotation: VirB10-like transmembrane secretion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 transmembrane" amino acids 30 to 49 (20 residues), see Phobius details PF03743: TrbI" amino acids 184 to 357 (174 residues), 180.1 bits, see alignment E=2.2e-57

Best Hits

KEGG orthology group: K03195, type IV secretion system protein VirB10 (inferred from 100% identity to sme:SMa1303)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Z02 at UniProt or InterPro

Protein Sequence (390 amino acids)

>SMa1303 VirB10-like transmembrane secretion protein (Sinorhizobium meliloti 1021)
MAQQDENRIPGERAETVSGRKIDNNPMLKRGAVALAVVAFVGFALWSMGGEGKRQDNAQP
ERVVIRQTTNFEPAKEKLEPVQPVPEVKLPTPVVTEEVKEEDPLLDSARRAPVIAYSSGQ
KNATSHRDSENPPISADSNFIPLDGDTMGQNTANADEQRFNGLLRPTRLEGSRAGTLGNR
NFIVAMGTSIPCVLETAMASDQPGFTSCVVNRDVLSDNGRVVLMEKGTQVVGEYRGGLQR
GQKRLFVLWYRAKTPNGVIVTLASPATDALGRAGVDGYVDTHWWERFGSALLLSIVGDAT
SYASSRLQDSDVDAQNTTSAGQQAAAVAVEQSINIPPTLNKHQGELVSIFVARDLDFSGV
YGLRVTGSKNKVLDRAVLGDFRPQSTLVTK