Protein Info for SMa1213 in Sinorhizobium meliloti 1021

Annotation: FixP1 di-heme cytochrome c

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 289 transmembrane" amino acids 34 to 56 (23 residues), see Phobius details TIGR00782: cytochrome c oxidase, cbb3-type, subunit III" amino acids 7 to 289 (283 residues), 361.9 bits, see alignment E=1.2e-112 PF14715: FixP_N" amino acids 13 to 59 (47 residues), 89.8 bits, see alignment 1.1e-29 PF13442: Cytochrome_CBB3" amino acids 112 to 194 (83 residues), 48.6 bits, see alignment E=1.3e-16 amino acids 207 to 282 (76 residues), 43 bits, see alignment E=7e-15 PF00034: Cytochrom_C" amino acids 113 to 197 (85 residues), 39.7 bits, see alignment E=1.5e-13 amino acids 207 to 285 (79 residues), 38 bits, see alignment E=5.2e-13

Best Hits

Swiss-Prot: 100% identical to FIXP_RHIME: Cbb3-type cytochrome c oxidase subunit FixP (fixP) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 100% identity to sme:SMa1213)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q05577 at UniProt or InterPro

Protein Sequence (289 amino acids)

>SMa1213 FixP1 di-heme cytochrome c (Sinorhizobium meliloti 1021)
MADKHKHVDEVSGVETTGHEWDGIRELNNPMPRWWVYSFYATIIWAIGYAIAYPSWPMLT
EATKGMLGYSSRAEVSVELAAAKAAQAGNLEQIASSSVEEIIANPQLQQFAVSAGASAFK
VNCAQCHGSGAAGGQGFPNLNDDDWLWGGKPQEIYQTIAHGVRHAPDGETRVSEMPPFGD
MLTPELMQQTAAYVVSLTQAPSQPHLVQQGKQVFADNCASCHGADAKGNREMGAPNLADA
IWLKGEGEQAVITQMKTPKHGVMPAWLPRLGDDTVKQLAVFVHSLGGGE