Protein Info for SMa1186 in Sinorhizobium meliloti 1021

Annotation: NosL copper chaperone

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 185 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF05573: NosL" amino acids 29 to 160 (132 residues), 173.8 bits, see alignment E=1.1e-55

Best Hits

Swiss-Prot: 49% identical to NOSL_ACHCY: Copper-binding lipoprotein NosL (nosL) from Achromobacter cycloclastes

KEGG orthology group: None (inferred from 100% identity to sme:SMa1186)

Predicted SEED Role

"Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL" in subsystem Denitrification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D4K1 at UniProt or InterPro

Protein Sequence (185 amino acids)

>SMa1186 NosL copper chaperone (Sinorhizobium meliloti 1021)
MKLTVTAILAATLFLAGCQKEEDTTMPSPYSLTADAMGRYCGMNVLEHPGPKGQIILQDI
PEPIWFSSARDTVAFTMLPEEPRDVAAIYVSDMGAAPSWQEPGAENWIDAKKAFYVIGSK
VRGGMGAEEAVPFSSERAARDFAAKNGGRVTGFAEIPKGYVLGTGTAEQGAAIETESHGE
AQIHG