Protein Info for SMa1185 in Sinorhizobium meliloti 1021

Annotation: NosY permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 53 to 74 (22 residues), see Phobius details amino acids 105 to 129 (25 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 171 to 191 (21 residues), see Phobius details amino acids 194 to 215 (22 residues), see Phobius details amino acids 222 to 240 (19 residues), see Phobius details amino acids 250 to 270 (21 residues), see Phobius details PF12679: ABC2_membrane_2" amino acids 5 to 275 (271 residues), 207.6 bits, see alignment E=3.6e-65 PF12730: ABC2_membrane_4" amino acids 17 to 174 (158 residues), 30.7 bits, see alignment E=4.5e-11 PF13346: ABC2_membrane_5" amino acids 60 to 193 (134 residues), 32.9 bits, see alignment E=7.4e-12

Best Hits

Swiss-Prot: 48% identical to NOSY_PSEST: Probable ABC transporter permease protein NosY (nosY) from Pseudomonas stutzeri

KEGG orthology group: K01992, ABC-2 type transport system permease protein (inferred from 100% identity to sme:SMa1185)

Predicted SEED Role

"Nitrous oxide reductase maturation transmembrane protein NosY" in subsystem Denitrification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D4K2 at UniProt or InterPro

Protein Sequence (275 amino acids)

>SMa1185 NosY permease (Sinorhizobium meliloti 1021)
MSNILTIAGKEIQEGMRNRWVLATTLLLTALALTLSFLGSVPTGSVGVDKLDVVIVSLSS
LTIFLVPLIALLLSHDAIVGEMERGTMLLLLSYPIGRREVVCGKFLGHLAILAFATLFGY
GAAAAALVATGSAVGPDSWQAFGSMIASSILLGAVFAAIGYLISSVARERATAGGIAIGI
WLFFVLIYDMALLGGLVAAQGLAIPTGLLNLLLLANPTDVYRVLNLGSGGASALSALGGV
ADHTGLSSPVLLAALGLWTLAPLGFATLIFSRREL