Protein Info for SMa0769 in Sinorhizobium meliloti 1021

Annotation: FixP2 Diheme c-type cytochrome

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 287 transmembrane" amino acids 32 to 52 (21 residues), see Phobius details TIGR00782: cytochrome c oxidase, cbb3-type, subunit III" amino acids 8 to 287 (280 residues), 350.6 bits, see alignment E=3.1e-109 PF14715: FixP_N" amino acids 11 to 57 (47 residues), 89.8 bits, see alignment 1.1e-29 PF13442: Cytochrome_CBB3" amino acids 110 to 192 (83 residues), 45.9 bits, see alignment E=8.9e-16 amino acids 205 to 280 (76 residues), 38 bits, see alignment E=2.6e-13 PF00034: Cytochrom_C" amino acids 112 to 195 (84 residues), 36.2 bits, see alignment E=1.9e-12 amino acids 205 to 252 (48 residues), 35 bits, see alignment 4.6e-12

Best Hits

Swiss-Prot: 81% identical to FIXP_SINMW: Cbb3-type cytochrome c oxidase subunit FixP (fixP) from Sinorhizobium medicae (strain WSM419)

KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 100% identity to sme:SMa0769)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92ZN7 at UniProt or InterPro

Protein Sequence (287 amino acids)

>SMa0769 FixP2 Diheme c-type cytochrome (Sinorhizobium meliloti 1021)
MTDKHIDEISGVETTGHEWDGIRELNNPLPRWWVYSFYATIIWAIGYAVAYPSWPMLTES
TKGVLGYSSRAEVSAELAEAKAAQAGNLERIASSAVEDIMANPELKQFAITIGASAFKVN
CAQCHGSGTAGGKGFTNLNDDEWLWGGKPEEIYQTIAHGIRYSGDGETRVSEMPAFTDTL
APREVRATAAYVASLTGTPSNPALVEPGKQLFAENCASCHGADAKGTREFGAPNLADAIW
LNGEGEQAIIDQMKSPKHGVMPAWLQRIGDPVVKELAVFVHSLGGGE