Protein Info for SMa0683 in Sinorhizobium meliloti 1021

Annotation: Cation efflux protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 42 to 64 (23 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details PF01545: Cation_efflux" amino acids 8 to 218 (211 residues), 87.4 bits, see alignment E=5.9e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMa0683)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92ZT7 at UniProt or InterPro

Protein Sequence (308 amino acids)

>SMa0683 Cation efflux protein (Sinorhizobium meliloti 1021)
MCNEQTFLRASIAATVVVAAFGIILGLLSGSFSITFDGVYSLADAGMTVLALWVSRLIAV
SATGDALSARMRDRFTMGFWHLEPIVLLLNGTLLMAIAVYALINALTSVLKGGHQLQFGF
AIAYAAVTVFVCAMMAVIGARANRGLRSNFIALDVKAWIMSGGIASALLVAFIIGHAVQE
TALHWMTLYVDPVVLAFVCIVIIPLPIGTVKSALADILLITPNELRARVERIADETVRKQ
GFLSYRAYVARVGRAKQIELHFIVPSNFPPQPVESWDQIRDEIGIAIGDEGHNRWLTVAF
TADERWAE