Protein Info for SMa0678 in Sinorhizobium meliloti 1021

Annotation: putrescine transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 51 to 73 (23 residues), see Phobius details amino acids 94 to 120 (27 residues), see Phobius details amino acids 127 to 150 (24 residues), see Phobius details amino acids 162 to 182 (21 residues), see Phobius details amino acids 195 to 214 (20 residues), see Phobius details amino acids 235 to 259 (25 residues), see Phobius details amino acids 278 to 302 (25 residues), see Phobius details amino acids 330 to 352 (23 residues), see Phobius details amino acids 361 to 383 (23 residues), see Phobius details amino acids 395 to 415 (21 residues), see Phobius details amino acids 421 to 439 (19 residues), see Phobius details TIGR04299: putrescine-ornithine antiporter" amino acids 14 to 442 (429 residues), 572.9 bits, see alignment E=2.7e-176 PF13520: AA_permease_2" amino acids 19 to 416 (398 residues), 168.9 bits, see alignment E=1.8e-53 PF00324: AA_permease" amino acids 29 to 414 (386 residues), 65.2 bits, see alignment E=4.8e-22

Best Hits

Swiss-Prot: 53% identical to POTE_HAEIN: Putrescine transporter PotE (potE) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03756, putrescine:ornithine antiporter (inferred from 100% identity to sme:SMa0678)

Predicted SEED Role

"Lysine/cadaverine antiporter membrane protein CadB" in subsystem Lysine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92ZU0 at UniProt or InterPro

Protein Sequence (452 amino acids)

>SMa0678 putrescine transporter (Sinorhizobium meliloti 1021)
MTEHSLNVAMEAASKKKMNLVQLTFIVAVNMMGSGIIMLPANMAQVGAISLLSWLVTAVG
SMAIAYGFAQAGLFNQRPGGMSAYAEDAYGKPGYFLVFLLYFLSLAVGNVAIGISAVGYL
AGFFPWLTSTPIATCVSLIILLWLTTVANFGGPRVTGRIGSITVWGVILPVGLLCIIGWA
WFSSEVFAAAWNPNGLTLVQGMGSSISLTLWAFLGMESAAQNSDAVENPKRDVPLACLFG
TLGAAIIYILSTTVIQGIVPNAELAASTGPFALAFATMFNPAIGSVVMALAVLACVGSLL
GWQFTIAQTARAAADERMFPSLFSRVNEMGAPVTGMIVMGVVQSLLALMTISPTLNEQFA
ALVNLAVVTNVLPYIISLSALFVMMRAAGVSESKFRLNSSIAIVGMLYSVFAIYASGKDA
VLGGMLVTGIAFIIYGLIAPRFTPRPGIVRTA