Protein Info for SMa0664 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 585 transmembrane" amino acids 151 to 172 (22 residues), see Phobius details

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SMa0664)

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92ZU8 at UniProt or InterPro

Protein Sequence (585 amino acids)

>SMa0664 hypothetical protein (Sinorhizobium meliloti 1021)
MTIAGRGSVRAGSPTALPTNTEILVQLDRIRLSAEFDVPDRARKFLAYIVGEAIAGRADR
IKAYSIATEVFGRDSSFDAQTDPVVRIEAGRIRRALERYYFVAGSNDPIVIKIPKGGYAP
AFEKRGGAPYQLSSGQAANVQSRSMSLEQTALWVSVATVGLLTCGLLANAFFGSAATTIE
SLTKPGGTRPNIPKLMVMPFEDLSQTPQSAMITRGLTDEVISNIAKFKEIVVVAGPAAPN
PHSAEREYPAFALEGRVRLDGDKLRLGIRLVQHSDGSVVWANTYDEVLQPRKIIELQQNA
AAAVASAIAQPYGIVFQANATHFMRSVPDDWQAYACTLAYYGYRGDLNPQTHASVQECLQ
HATTQFPDYATAWALLSLTYVDELRFRYRLNRSTTVSLSHAIEAAARAVELDPQNVRALQ
AEMLTLFFRGEVNAALTVGARAYAINPNDTELSGEYGFRLALSGQWRSGCDLVSKTVASN
PGPVGYFEAALAVCCYIEHDYVAAERWARSADLHANPVYHVILLAILGKLGKMDLARAER
EWLEINVPGFLENARNEVALRIHRPEDQKHFIEGLRQAGVPIPGK