Protein Info for SMa0501 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 228 transmembrane" amino acids 20 to 46 (27 residues), see Phobius details amino acids 63 to 85 (23 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 148 to 170 (23 residues), see Phobius details amino acids 190 to 217 (28 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 14 to 111 (98 residues), 105.2 bits, see alignment E=1.1e-34 PF00528: BPD_transp_1" amino acids 35 to 209 (175 residues), 88 bits, see alignment E=3.4e-29

Best Hits

Swiss-Prot: 33% identical to GLNP_ECOL6: Glutamine transport system permease protein GlnP (glnP) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 100% identity to sme:SMa0501)

MetaCyc: 33% identical to L-glutamine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-12-RXN [EC: 7.4.2.1]

Predicted SEED Role

"Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930D4 at UniProt or InterPro

Protein Sequence (228 amino acids)

>SMa0501 ABC transporter permease (Sinorhizobium meliloti 1021)
MDYTFQFGPLLNYLPQIVSGLWLTIGLSFVGIFGGIALGIFCAVMSTLSSPIPRLLVRLY
VEVVRNTPLLVQIFVIFFGLPNIGIRLSPLTSVFIALVLNNGGYVAEIVRGGIEATHRSQ
VEAAESLGLSYFQTLRYVILPPALEKVFTPVVSQCVLLMLSTSLVSAIGVEDLTGAAMIA
SSETFRTMEIYLVVAMVYVVLNFVFRAVLNVAGLMIFTRSRRRLLGRA