Protein Info for SMa0467 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 transmembrane" amino acids 31 to 52 (22 residues), see Phobius details amino acids 120 to 144 (25 residues), see Phobius details amino acids 155 to 181 (27 residues), see Phobius details amino acids 198 to 219 (22 residues), see Phobius details amino acids 251 to 277 (27 residues), see Phobius details amino acids 304 to 327 (24 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 25 to 124 (100 residues), 41.6 bits, see alignment E=1.3e-14 PF00528: BPD_transp_1" amino acids 136 to 332 (197 residues), 126.9 bits, see alignment E=8.1e-41

Best Hits

Swiss-Prot: 39% identical to GSIC_SHIFL: Glutathione transport system permease protein GsiC (gsiC) from Shigella flexneri

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 100% identity to sme:SMa0467)

MetaCyc: 39% identical to glutathione ABC transporter membrane subunit GsiC (Escherichia coli K-12 substr. MG1655)
RXN0-11 [EC: 7.4.2.10]

Predicted SEED Role

"Nucleoside ABC transporter, permease protein 1"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930F4 at UniProt or InterPro

Protein Sequence (338 amino acids)

>SMa0467 ABC transporter permease (Sinorhizobium meliloti 1021)
MHRAAPSTGLTAISGGANGGSSLVVFITRRFAVTIPLLLIISFGVFALIHIAPGDPVSSL
LGARASDPATLAAIRARYHLDDSLLVQYGTWLSQVIRGDLGVSILGNRSVTSTIADRLGV
TIFLSLMSTTLVLGLGILLGALAAFRRGTGLDRTVVMFSVFGISSPAFVTGIFFLYVFGV
LLHWFPTFGAGTGFLDRAWHLALPALALAASTMAIVVKITRAAVIEELARDYVTFARARG
VSSRRILLAYVLRNSLIPVITAAGLIVIGILAGAIYVEVTFSLPGLGALMIDAVQKRDIP
TIQGITLLFSAFVVLVNLAVDVIYTLIDPRIRFGRVGS