Protein Info for SMa0392 in Sinorhizobium meliloti 1021

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details PF01547: SBP_bac_1" amino acids 55 to 309 (255 residues), 51.1 bits, see alignment E=4e-17 PF13416: SBP_bac_8" amino acids 67 to 337 (271 residues), 150.7 bits, see alignment E=1.6e-47 PF13343: SBP_bac_6" amino acids 144 to 327 (184 residues), 49.1 bits, see alignment E=1.1e-16 PF13531: SBP_bac_11" amino acids 150 to 311 (162 residues), 26 bits, see alignment E=1.5e-09

Best Hits

KEGG orthology group: K02055, putative spermidine/putrescine transport system substrate-binding protein (inferred from 100% identity to sme:SMa0392)

Predicted SEED Role

"Spermidine/putrescine-binding periplasmic protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930I7 at UniProt or InterPro

Protein Sequence (371 amino acids)

>SMa0392 ABC transporter substrate-binding protein (Sinorhizobium meliloti 1021)
MSHEKFLSAQIGRRTLLASMAAAGASAGLSTLGVSRAFAQEPEKPAEIIVRAWGGSWVDA
LKAGVSDSFTKMTGIAVRHDLTEDNEIQPKVWAAVAQKRVPPIHINWDTTTNATKSALRG
VTEDLSDLPNLKNATDLAKPVGLDGYPIVNTYGYVYVLAYRPSAFPNGAPKSWKDLLDPK
LKGRIALYNDGIGFHFPAQVAGGGKLEDIPANMQPAWDFISKIKEQQPLLGEDPDFTTWF
QKGEIDAACTISTNAREAKKNGIEIAWVVPEEGAKFDTDGLWIPKGLPENELYWAKQYIN
HALTKEAQQIWLDGLGLPGVIPGITPPADLVGDPSYPTTEEDFKQLIRISAKVQVENESQ
WFAKFKEIMQG