Protein Info for SMa0273 in Sinorhizobium meliloti 1021

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 34 to 292 (259 residues), 154.7 bits, see alignment E=3.5e-49 PF00532: Peripla_BP_1" amino acids 69 to 246 (178 residues), 31.3 bits, see alignment E=1.5e-11

Best Hits

KEGG orthology group: K10439, ribose transport system substrate-binding protein (inferred from 100% identity to smk:Sinme_5349)

Predicted SEED Role

"Xylose ABC transporter, periplasmic xylose-binding protein XylF" in subsystem Xylose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930Q0 at UniProt or InterPro

Protein Sequence (321 amino acids)

>SMa0273 ABC transporter substrate-binding protein (Sinorhizobium meliloti 1021)
MKSIIRKAGLLLSTATLVLAQPLGTAQAQEKRIVAVSIPAATHGWTGGVVYHAEQAEKEV
EAAFPNVDVVLSTASSATAQVSALEDLSATRKLDALVILPFTSEELTGPVEQIKKNGTFI
SVVDRGLTDPTIQDLYVAGDNIAVGANTARWLSDKLGGQGEIVVLRGIPTVIDDERIKGF
SDVIDKTNIKILDIQYANWNQDEAFKLMQDYLAKYPKIDAVWANDDDMLLGVIEAVDRAG
RKDIKYALGGNGMKQVIEMVKEGNERTPVSTPYPPSMIKSAIYMTAAQFAGQAPMRGSFL
LGAPLITPENADQFYFPDSPF