Protein Info for SMa0270 in Sinorhizobium meliloti 1021

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 530 PF00005: ABC_tran" amino acids 36 to 185 (150 residues), 108.6 bits, see alignment E=4e-35 amino acids 286 to 439 (154 residues), 70.8 bits, see alignment E=1.9e-23

Best Hits

Swiss-Prot: 43% identical to RBSA1_STRAW: Ribose import ATP-binding protein RbsA 1 (rbsA1) from Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

KEGG orthology group: K02056, simple sugar transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to sme:SMa0270)

Predicted SEED Role

"D-xylose transport ATP-binding protein XylG" in subsystem Xylose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930Q2 at UniProt or InterPro

Protein Sequence (530 amino acids)

>SMa0270 ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MNAALPSNAVAPPPNRAVAALAAEGLGKAYGPITVLSDVTLEVHAGEVHAIIGENGAGKS
TLMKLLSGHVVPTAGHLLLEGKSVEFRNAVEAENAGIVLVHQEILLASDLTVAENLYLGR
EVGRGLLVNDKAMNSRAAELLARVGSAARPRDRVGELPLAQRQLVQIARALLDERKVIIF
DEPTAVLANDEVAALLDIVRSLRDHGVAVLYISHRLDEVQALADRITVLRDGRMIGTWPA
AGLGQREMAELMVGRELDMLYPHKRSATTAAPILSVTNLAIDHGSQTVSFSVSPGEVLGI
GGMVGAGRTELIEGLMGLRPSEAESIVLNGREIGSRSVRTLMDAGLVYLTEDRKGKGLLL
EEKLGPNLTLQALDTINPGVFLDKQGELSRLRKAVADYDIRVRSMRLEASQLSGGNQQKL
LLAKVMMADPSVIIIDEPTRGIDIGNKSQIYDFIDGMVRAGKACIVISSEMPELVGLADR
VLVMRAGRIVAELRGDEINEENVVYAATTGGCADVGEEKHDRSDSNTRTN