Protein Info for SMa0224 in Sinorhizobium meliloti 1021

Annotation: Permease, MFS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 490 transmembrane" amino acids 16 to 40 (25 residues), see Phobius details amino acids 55 to 74 (20 residues), see Phobius details amino acids 85 to 102 (18 residues), see Phobius details amino acids 114 to 135 (22 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 171 to 194 (24 residues), see Phobius details amino acids 204 to 223 (20 residues), see Phobius details amino acids 229 to 251 (23 residues), see Phobius details amino acids 271 to 293 (23 residues), see Phobius details amino acids 305 to 326 (22 residues), see Phobius details amino acids 337 to 356 (20 residues), see Phobius details amino acids 362 to 388 (27 residues), see Phobius details amino acids 409 to 429 (21 residues), see Phobius details amino acids 461 to 484 (24 residues), see Phobius details PF07690: MFS_1" amino acids 25 to 414 (390 residues), 154.4 bits, see alignment E=3.8e-49

Best Hits

KEGG orthology group: K08167, MFS transporter, DHA2 family, methyl viologen resistance protein SmvA (inferred from 100% identity to sme:SMa0224)

Predicted SEED Role

"FIG01073952: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930S5 at UniProt or InterPro

Protein Sequence (490 amino acids)

>SMa0224 Permease, MFS (Sinorhizobium meliloti 1021)
MPMTDTSLPRTVDRTAWLGLIAILPLVLLVAMDGSILYLAMPHVTSALMPTADQALWILD
IYGFVVGSLLIAFGNIGDRYGRLKLIITGAAVFGAGSLGAAYSQTPEQLIASRALMGLGG
ATLLPSGLAIVSALFPDPRLRAQAIGIFAATFAAGFAIGPLIGGMLLRQFAWGAVFLINV
PVVIGFMIGAPILLREVRSTVGGSIDLASLVLSFAGILLFTYSLKNAAAYGFTPTQIVAG
AAGIFALALFARRQTKLEYPLLDLGLFRDRIFSIAILTGLLSLVVWSAAGYLSGVYLQSV
LGIDVFAAALLTLPGAIVLTATCVATARIVERIGRKTALVATHLLIGAGVFLLLFTTTET
GIAVFIASTMIAGIGYGLSFSLVADIAVSAVPANRAGAAGSIAETSNELGNALGISLLGS
LATLSFRLFGPGVAGTLDETLDQPGLAHQSLIQAQEAFLTGMHVAIGTGGLLTLAVGMVA
WLWLPSKLPE