Protein Info for SMa0203 in Sinorhizobium meliloti 1021

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 31 to 291 (261 residues), 179.6 bits, see alignment E=4.4e-57

Best Hits

KEGG orthology group: K02058, simple sugar transport system substrate-binding protein (inferred from 100% identity to sme:SMa0203)

Predicted SEED Role

"ABC transporter, substrate binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930T8 at UniProt or InterPro

Protein Sequence (338 amino acids)

>SMa0203 ABC transporter substrate-binding protein (Sinorhizobium meliloti 1021)
MTIRKMLLASAAITCAAMPASAFADTSAKKIALSNNYAGNSWRQAMLTSWEKVTGEAVKA
GIVASADAFTTAENQATEQAAQIQNMILQGYDAIVLNAASPTALNGAVKEACDAGITVVS
FDGIVTEPCAWRIAVDFKEMGRSQVEYLSNKLPDGGNLLEIRGLAGVFVDDEISAGIHEG
VKQFPQFKIAGSVHGDWAQDVAQKAVAGILPSLPDIVGVVTQGGDGYGAAQAIAATDRKM
PIIVMGNREDELKWWKEQKDANGYETMSVSIAPGVSTLAFWVAQQILDGKEVKKDLVVPF
LRIDQDNLEANLANTQAGGVANVEYTQEDAIKVIESAK