Protein Info for SMa0130 in Sinorhizobium meliloti 1021
Annotation: fatty acid desaturase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K10255, omega-6 fatty acid desaturase (delta-12 desaturase) [EC: 1.14.19.-] (inferred from 100% identity to smk:Sinme_5432)Predicted SEED Role
"Beta-carotene ketolase (EC 1.14.-.-)" in subsystem Carotenoids (EC 1.14.-.-)
KEGG Metabolic Maps
- 1,4-Dichlorobenzene degradation
- Ascorbate and aldarate metabolism
- Benzoxazinone biosynthesis
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of steroids
- Biosynthesis of terpenoids and steroids
- Biosynthesis of unsaturated fatty acids
- Brassinosteroid biosynthesis
- Carotenoid biosynthesis - General
- Diterpenoid biosynthesis
- Limonene and pinene degradation
- Naphthalene and anthracene degradation
- Phenylpropanoid biosynthesis
- Sphingolipid metabolism
- Tryptophan metabolism
- Ubiquinone and menaquinone biosynthesis
- alpha-Linolenic acid metabolism
- gamma-Hexachlorocyclohexane degradation
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.14.-.- or 1.14.19.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q930X6 at UniProt or InterPro
Protein Sequence (355 amino acids)
>SMa0130 fatty acid desaturase (Sinorhizobium meliloti 1021) MSAHVYPPASLVEDNAGAWLKTLAKYRQPRLGRSAFELFVTLVPFAIFWAAACFSLANGF WPGLIAILPASAFLLRLFMIQHDCGHGSFFSRRGLDDWTGRLLGVLTLTPYDYWRRAHAA HHATAGNLDERGVGDITTLTITEYCALSPIKRLGYRLYRHPLVMFGIGPAWLFLFKQRLP FGMMNSGALPWISTMATNFAIVTLAALMVWAVGLGTFLLIHLPVVLLAGAAGVWLFYVQH QFEETHWSAGEDWRFPQAALHGASHYDLPPVLRWLTGNIGIHHVHHLSSRIPYYRLPEVL RDHPQLAGIGRITLWDSLKCVRLVLWDDRRRRLVSFHDAAGSLRRSLTEDGRKTK