Protein Info for SMa0105 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 102 to 125 (24 residues), see Phobius details amino acids 136 to 158 (23 residues), see Phobius details amino acids 178 to 194 (17 residues), see Phobius details amino acids 232 to 253 (22 residues), see Phobius details amino acids 280 to 304 (25 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 1 to 104 (104 residues), 40.8 bits, see alignment E=2.3e-14 PF00528: BPD_transp_1" amino acids 117 to 309 (193 residues), 130.7 bits, see alignment E=5.5e-42

Best Hits

Swiss-Prot: 41% identical to Y209_BRUME: Putative peptide transport system permease protein BMEII0209 (BMEII0209) from Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 100% identity to smk:Sinme_5451)

MetaCyc: 33% identical to murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppB (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]; 7.4.2.6 [EC: 7.4.2.6]

Predicted SEED Role

"Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q930Z2 at UniProt or InterPro

Protein Sequence (311 amino acids)

>SMa0105 ABC transporter permease (Sinorhizobium meliloti 1021)
MLRFTLRRVLQIIPTVVVVALLIFVIFSVVPGTFAASLFADGRRAADPQMIARLNEEFGL
NKPLMERFVTYVTDLAQFDLGTSFRTRQPVIDLINDRMWASLQLAIAAMIFALVISVPLG
FVAALRPGSVLDTVTMIGAVSGLSMPQFWLGLLMMYLFALQLNWLPSFGYGDGSFRNLIL
PAVTLGVTPLALLARTTRAGVLDVLNADFIRTAHSKGMSEAKVVRWHVARNALVLIVTTV
GLQFGSLIGQAVVIEKLFAWPGIGSLLVDSVASRDIPVVQGTILVIVLWFLVINTAVDLI
YAAIDPRIKQE