Protein Info for SMa0079 in Sinorhizobium meliloti 1021

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 63 to 84 (22 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 146 to 169 (24 residues), see Phobius details amino acids 189 to 211 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 13 to 110 (98 residues), 95.5 bits, see alignment E=1.2e-31 PF00528: BPD_transp_1" amino acids 34 to 214 (181 residues), 77.8 bits, see alignment E=4.7e-26

Best Hits

Swiss-Prot: 34% identical to GLNP_SHIFL: Glutamine transport system permease protein GlnP (glnP) from Shigella flexneri

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 100% identity to sme:SMa0079)

MetaCyc: 34% identical to L-glutamine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-12-RXN [EC: 7.4.2.1]

Predicted SEED Role

"polar amino acid ABC transporter, inner membrane subunit"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q931A5 at UniProt or InterPro

Protein Sequence (222 amino acids)

>SMa0079 ABC transporter permease (Sinorhizobium meliloti 1021)
MYEFNFAPVLASFDQLLVGAWLTVRLSCAAMLIGLVVSVFCAWGKTAGPAILRHVIDGYI
EIIRNTPFLVQIFFIFFGMPSLGLRLSPNSAALLALVVNFGAYGTEIIRAGIESIHKGQV
EAGWALGLSRPQIFRYVVMKPALRTVYPALTSQFIYLMLNTSVVSVISADDLAAAGNDLQ
SATFASFEVYIAVTLIYLALSVGFSALFYALEKAAFKYPLGR