Protein Info for SM_b21593 in Sinorhizobium meliloti 1021

Annotation: sugar uptake ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 transmembrane" amino acids 9 to 30 (22 residues), see Phobius details amino acids 69 to 94 (26 residues), see Phobius details amino acids 105 to 127 (23 residues), see Phobius details amino acids 139 to 161 (23 residues), see Phobius details amino acids 182 to 206 (25 residues), see Phobius details amino acids 243 to 261 (19 residues), see Phobius details PF00528: BPD_transp_1" amino acids 87 to 268 (182 residues), 60.8 bits, see alignment E=7.3e-21

Best Hits

KEGG orthology group: K02026, multiple sugar transport system permease protein (inferred from 100% identity to smk:Sinme_4679)

Predicted SEED Role

"Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92UR0 at UniProt or InterPro

Protein Sequence (275 amino acids)

>SM_b21593 sugar uptake ABC transporter permease (Sinorhizobium meliloti 1021)
MSDTFRNRLMLAVALVLAAIYLFPLYWMYITALKTGSAMFATPPKFWPSEPQWSIYAFVW
ESRNMARYLWNSLVIAFGSVALIAVLGVGCAYVLARYRNVWVDIGLFLILMLQVLPASLM
VTPIFVGFSQVGLLDTPRLAVILAIAAKSMPFFVVLVRATFMSVPMELEEAALVDGNSRI
GAFFNIVLPLARNGILVSAILIFMQAFGEFVYSKSMIQAVELQPASVGLNTFMGPNTNEW
NNIMAYATIYVTPILAAFILLQRRIVSGLTSGALK