Protein Info for SM_b21498 in Sinorhizobium meliloti 1021
Annotation: acriflavin resistance protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 60% identical to BEPG_BRUSU: Efflux pump membrane transporter BepG (bepG) from Brucella suis biovar 1 (strain 1330)
KEGG orthology group: None (inferred from 62% identity to alv:Alvin_0257)Predicted SEED Role
"RND efflux system, inner membrane transporter CmeB" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q92U15 at UniProt or InterPro
Protein Sequence (1077 amino acids)
>SM_b21498 acriflavin resistance protein (Sinorhizobium meliloti 1021) MISEIFIDRPRFAAVISIVLTLAGLIALTRLPIAQFPDIVPPQVSVTASYPGAGADVVEA TVAQPLESKVVGVDNMLYMKSTSGADGTYSLTVTFAVGTDPDIATVNVQNRVALAEPVLP AEVKQSGVSVQKRSSSLMQVIAIHGENDEFDNLFLSNYATINVLDTIKRVPGVGDATLFG AQDYSMRVVLDIDRLTNLGLTPTDVINALKTQNVQAAIGRIGAQPMTDDPLFQLNIQTQG RLTDPAQFEDVVLRAEPDGSFVRIRDVARVELGSVSADSTARINGKPVAMIGTYQAPGAN ALAATEGVQQAMNRLAAAFPEGLTYTVSYDTSDFVQASVENVEHTLLEAFALVIIVVFLF LGNWRAALIPLIAVPVALVGTFAVILAMGFSLNTVSLLALVLAIGIVVDDAIVVVENVER VMEENPGMSAAQAARLAMGEITGAIVAITLVLLSVFVPVAFIPGLSGQLFQQFAVAVSVS MVISAINALTLSPALCAILLKPHHGPKRGILGWISRGIDRTRNGYAHVAGSIARRAIIGV ILLAVAIGASGWLFRIVPTGFLPSEDQGAFFAEIRLPEGASFNRTDAVVREVETMLGGIE GVANVTTVTGYSFLDGIAKSSSAFAIVTMKPFAERQDESASVNAAIGTVMAKGAAIRNAQ VFAFNLPPIIGLGTGSGFEYQLLDLQGRSPAELAATAGGLMVAANQNPQLGPTFSTYSAS SPQLYLNLDRDRLQALGVSVSDLFATLQGTLGSYYVNDFNLFGRSWKVTMQAAEADRDAV DDISRLHVRNAAGDMVPVASVARVDYIVGPQSIVRYNNYRSITLNGQPAPGISSGQALAA MEQVSAATLPPGYSFEWTGTALQELEAAGQTTVILALALLFAYLFLVALYESWTIPIPVL LSVSVGVAGALVAVLVAGLSFDIYAQIGLVVLIALASKNAILIVEFAKFQREKGATIVDA AVEGARTRFRAVMMTSFAFIVGLIPLVTADGAGMLSRRAVGTGVAGGMLAASLLGIFIIP ALYVVFQWLRERGHKLAGLSSHAAGEAPHAATESAESVKPATGQQAQTVGQDRNVPD