Protein Info for SM_b21466 in Sinorhizobium meliloti 1021

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 586 transmembrane" amino acids 24 to 48 (25 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 149 to 179 (31 residues), see Phobius details amino acids 253 to 271 (19 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details TIGR01842: type I secretion system ATPase" amino acids 19 to 562 (544 residues), 740.1 bits, see alignment E=7.1e-227 PF00664: ABC_membrane" amino acids 29 to 285 (257 residues), 73.7 bits, see alignment E=2.1e-24 PF00005: ABC_tran" amino acids 354 to 500 (147 residues), 97 bits, see alignment E=1.6e-31

Best Hits

Swiss-Prot: 100% identical to PRSD_RHIME: Type I secretion system ATP-binding protein PrsD (prsD) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K12539, ATP-binding cassette, subfamily C, bacterial PrsD (inferred from 100% identity to sme:SM_b21466)

Predicted SEED Role

"CELL PROCESSES; Transport of small molecules; amino acids, amines, peptides"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7ANN4 at UniProt or InterPro

Protein Sequence (586 amino acids)

>SM_b21466 ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021)
MPEFMATSKGRNADPAAALRDCRAAFIGVGVASALVNLLYLTGSFFMLEVYDRILPSRSI
PSLIALSLLALLLYAFQGAFELIRGRMLVRIAGALDESLNGRIYRAIVKAPLKLRMQGDG
LQALRDFDQVRSFLSGVGPAALFDLPWLPFYIAICFLFHPVIGLIAIIGGLILTLLTYLT
NRGTQAPAKKASEAGGLRNVFAQASQRNAEVVHAMGMSARLTALWERRNTEFRDENRRTS
DIGNGYGALSKVFRMALQSGVLAAGAVLVIRGEASPGIIIAGSILTARALAPVELAIGNW
RGLVAARQSWQRLKELLNALPEADAPLQLPDPHERLTVEGLASGPPAAQRLVVSDVNFTV
RAGGAVGVIGPSASGKSSLARAILGIWPAYRGSVRLDGAALDQWDSDALGKHVGYLPQDV
ELFAGTIAQNICRFAEDATSEAIVAAAKAARVNDLILRLPNGYDTEIGDGGMTLSAGQRQ
RVALARALYGDPFLVVLDEPNSNLDAEGEQALSEAIMSVRSRGGIVIVVAHRPSALASVD
LVLMMNEGRMQAFGPKEQVLGQVLRPQQVERQNALKVVAEGQEAKQ