Protein Info for SM_b21463 in Sinorhizobium meliloti 1021

Annotation: glycosyl hydrolase, 6-phospho-beta-glucosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF02056: Glyco_hydro_4" amino acids 2 to 177 (176 residues), 137.1 bits, see alignment E=5.1e-44 PF11975: Glyco_hydro_4C" amino acids 190 to 436 (247 residues), 160.3 bits, see alignment E=6.8e-51

Best Hits

KEGG orthology group: K01222, 6-phospho-beta-glucosidase [EC: 3.2.1.86] (inferred from 100% identity to sme:SM_b21463)

Predicted SEED Role

"FIG01074355: hypothetical protein"

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.86

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92U51 at UniProt or InterPro

Protein Sequence (461 amino acids)

>SM_b21463 glycosyl hydrolase, 6-phospho-beta-glucosidase (Sinorhizobium meliloti 1021)
MKLTLIGGGGVRAPLFVGSALRRAERSGLSEICLQDINERKLELFGRISQELARRTQSPV
RITMAADAERALDGARYVVTTVRPGNEDGRIKDERIALAHGVLGQETTGPGGFAMALRSI
PVILKYAEILKKVSPDAWLFNFTNPAGLVTQALQNEGYHRTVGICDGANGAQEALAHWHK
VQQNDVRCEVYGLNHLSFTRRATIDGKEVLQPLLDDDGFLRSTSQRMFDASLIRSQRNWI
NEYLYYYYYAEKAVEALKADARTRGEEVKDLNAALITRLSAMDLNADAERRSPPNYAYER
RRNATYMHYALTDAPSMEEADRLVEGLAAAQTGEEGEGYAGVALNLVDALETGKPCYTGL
NVRNEGAIEGLRNDDVVEVSCLVDGEGIRPLKIGAMPEAQSQIVHNVKRYERLAVRAIRE
RSRDLAVQALMAHPLVLSYSRAVPLVDEYLAAHAEFAGEWS