Protein Info for SM_b21206 in Sinorhizobium meliloti 1021
Annotation: ABC transporter ATP-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01990, ABC-2 type transport system ATP-binding protein (inferred from 100% identity to sme:SM_b21206)Predicted SEED Role
"ABC transporter multidrug efflux pump, fused ATP-binding domains"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q92V45 at UniProt or InterPro
Protein Sequence (582 amino acids)
>SM_b21206 ABC transporter ATP-binding protein (Sinorhizobium meliloti 1021) MPAPATEPGTAPFVRLTGVTKRFGTARPALDAVAGEIFGGRVTGLVGPDGAGKTTLIRLM TGLMLPDAGTIEVLGYDTRRDPASIQAAIGYMPQRFGLYEDLSVQENLDLYADLRGLPKT ERSRTFGELLDFTDLARFTTRLAGKLSGGMKQKLGLACALLRKPRLLLLDEPGVGVDPIS RRDLWKMVGNLRTEGIGVVWSTAYLEEAEACDHVFLLNQGSLMFSGPPAEMTGRVEDRVF RLSGIRGRRREALARFLEDEGVVDGVIQGEAIRLVMKAGLSPPPLGDTADAVDAAVTPPR FEDAFVDMLGGGPGGRSRLAETQREFTEDAGRPVIEARGLTKRFGDFTAADNITFDIPRG EIFGLLGPNGAGKSTTFKMLCGLLKPSAGEGRVAGFDLRRNAPEARNRLGYMAQKFSLYG DLSVIQNFNFFAGVYGLSGARKRERIGLMSEIFDFRTILDMSAKDLPLGLKQRLALACSV LHEPEVLFLDEPTSGVDPITRREFWTHINGLVEKGVTVLVTTHFMDEAEYCDRISLIYRG RSIALGSPDDMKARVAGKDLPDPTMEDAFIALIQGSEAKEAA