Protein Info for SM_b21187 in Sinorhizobium meliloti 1021

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 PF13411: MerR_1" amino acids 9 to 77 (69 residues), 74.2 bits, see alignment E=2.5e-24 PF00376: MerR" amino acids 11 to 46 (36 residues), 45.7 bits, see alignment 1.6e-15 PF13560: HTH_31" amino acids 99 to 155 (57 residues), 45.7 bits, see alignment E=2.3e-15 PF13443: HTH_26" amino acids 103 to 156 (54 residues), 22.6 bits, see alignment E=3.7e-08 PF07883: Cupin_2" amino acids 201 to 270 (70 residues), 69.9 bits, see alignment E=4.1e-23 PF05899: Cupin_3" amino acids 214 to 257 (44 residues), 25.7 bits, see alignment 2.7e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_4851)

Predicted SEED Role

"probable MerR-family transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92V63 at UniProt or InterPro

Protein Sequence (276 amino acids)

>SM_b21187 LacI family transcriptional regulator (Sinorhizobium meliloti 1021)
MGGIGTIRYKVAEAARLAGVSASTLRLWETQGLVVPERSVTGHRQYTDADLARLKRISWF
RSERGLNPAAIREALEAESAFTEDENGSAMPTEDNGDMQVGRKLRSLRHAAGKTLEQVAG
DIGIAASVLSTLERTSQGVSVAVLHNLAEYFGTTVSSLSGEEQTRARALVRAGEWRNWPR
TTPGVTVQLLAEGKNQMDCHRFVLAPGASSEGAYRHEGEEFVYVLSGHVEFVLDSDQFYD
LHPGDSLYFESRRRHAWSNRHDGETVLLWINTPPTF