Protein Info for SM_b21134 in Sinorhizobium meliloti 1021

Annotation: amino acid processing enzyme, low specificity D-threonine aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 PF01168: Ala_racemase_N" amino acids 12 to 229 (218 residues), 81 bits, see alignment E=1.1e-26 PF14031: D-ser_dehydrat" amino acids 244 to 334 (91 residues), 81.9 bits, see alignment E=4.3e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SM_b21134)

Predicted SEED Role

"low-specificity D-threonine aldolase" in subsystem Serine-glyoxylate cycle or Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92VI9 at UniProt or InterPro

Protein Sequence (352 amino acids)

>SM_b21134 amino acid processing enzyme, low specificity D-threonine aldolase (Sinorhizobium meliloti 1021)
MTLPIETPAVLVDLDIARRNVLAFQAYADRHGIRVRPHIKTHKLPQMAELQLDAGAIGIT
CQKVTEAEAMVDGGARIKDVLITYNLLGEQKLARLARLNERVTVSVVADNATVVDGLAAF
FADAGKPLTVLVECNTGADRCGVGTPSEAARLARRIAEAPGLRFGGLMTYPPADGAARVQ
AFMSDAKRLIEAEGLEVPCITSGGTPGMMQAAEAPIASEHRPGTYIYNDRSLVARGVASW
EDCALTVLATVVSVPSENRAIIDAGSKVLTSDLLGLTGYGHVLGRDDIRIDQLSEEHGRL
VSDGQIGLQVGELVRIVPNHACVVTNMVDAVHVIEGGAPKGTWPVVARGRVL