Protein Info for SM_b20975 in Sinorhizobium meliloti 1021

Annotation: amino acid uptake ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 549 transmembrane" amino acids 12 to 28 (17 residues), see Phobius details amino acids 48 to 68 (21 residues), see Phobius details amino acids 78 to 96 (19 residues), see Phobius details amino acids 142 to 162 (21 residues), see Phobius details amino acids 174 to 199 (26 residues), see Phobius details amino acids 208 to 228 (21 residues), see Phobius details amino acids 236 to 255 (20 residues), see Phobius details amino acids 347 to 368 (22 residues), see Phobius details amino acids 380 to 399 (20 residues), see Phobius details amino acids 418 to 437 (20 residues), see Phobius details amino acids 465 to 485 (21 residues), see Phobius details amino acids 519 to 540 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 357 to 544 (188 residues), 71.5 bits, see alignment E=3.9e-24

Best Hits

KEGG orthology group: K02029, polar amino acid transport system permease protein K02030, polar amino acid transport system substrate-binding protein (inferred from 100% identity to sme:SM_b20975)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92UM5 at UniProt or InterPro

Protein Sequence (549 amino acids)

>SM_b20975 amino acid uptake ABC transporter permease (Sinorhizobium meliloti 1021)
MSFLRSVRPSNLIILTALPFIIYLFASSGDYQRSLRAILGVENGSSAFVPGFLALLVAFG
SGVAVLVFSRAKAPRPRLALAAAVLNLAAAASVLLSDAVHPYLASVVANAVDPFTSDLVV
KGLSPRQLTDAADMTLRGIEAVLFPAYFALTLLGFMLFFGAGKASTPESIMRRLGALSIG
LVSSGGLLFILFFAHIAFAAGVATTVRAAIAAYLLAAIIGLIWVGLLQLHYTARTSIIFA
LATLGLTLVAAWFLLQPRTAYVLAGRLDGTVAIVSNTPSGLIGAVRFGQYPGAPGEEAAV
RTFLGPAEAVAAMEKNEVTAALLPSAAVPGGLPLLWETAALNDRDRAAGITFAVLAIILG
LLTFGGYLHRRHPLAIGSEFVVDTIRGIPMLVIVLYVGLPLSGALKDATQGVLDPPNLMR
GIVAMALAYSAYLAEIFRSGINAIPIGQIEAARSIGLNRWQTARLVVLPQAFRIIIPPLG
NELIAILKDTSLLSILSIRDITQRMREFQSASFLPFAPYNSAAIFYIFLTLAAASLINMI
ERKYDIKHR