Protein Info for SM_b20860 in Sinorhizobium meliloti 1021

Annotation: non-heme haloperodidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 PF00561: Abhydrolase_1" amino acids 24 to 258 (235 residues), 120.3 bits, see alignment E=2.3e-38 PF12146: Hydrolase_4" amino acids 24 to 124 (101 residues), 52.7 bits, see alignment E=7.6e-18 PF12697: Abhydrolase_6" amino acids 25 to 243 (219 residues), 74.3 bits, see alignment E=4.7e-24

Best Hits

Swiss-Prot: 68% identical to PRXC_BURPY: Non-heme chloroperoxidase (cpo) from Burkholderia pyrrocinia

KEGG orthology group: None (inferred from 99% identity to smk:Sinme_4564)

Predicted SEED Role

"Non-heme chloroperoxidase (EC 1.11.1.10)" (EC 1.11.1.10)

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.10

Use Curated BLAST to search for 1.11.1.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92UH7 at UniProt or InterPro

Protein Sequence (276 amino acids)

>SM_b20860 non-heme haloperodidase (Sinorhizobium meliloti 1021)
MTSITTSDGVQIFYKDWGPKSAQPIVFHHGWPLSSDEWDNQMLFFLGRGFRVIAHDRRGH
GRSSQASEGHDMDHYVSDVAALIDHLDLRNAIHVGHSTGGGEAARYVARFGKNRVAKLIM
IAAVPPLMLKTAANPGGLPLEVFDGLRSQLAANRSQFYRDFPSGPFYGYNRPGAEPSQAV
ISNWWRQGMMGGAKAHYEGIKAFSETDFTEDLKSISVPTLVLHGDDDQIVPIGTSSPLSA
KLIKAATLKIYEKLPHGLCTTHADIVNADILAFVTA