Protein Info for SM_b20604 in Sinorhizobium meliloti 1021

Annotation: branched-chain amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 537 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 245 to 272 (28 residues), see Phobius details amino acids 279 to 298 (20 residues), see Phobius details amino acids 304 to 324 (21 residues), see Phobius details amino acids 336 to 354 (19 residues), see Phobius details amino acids 386 to 404 (19 residues), see Phobius details amino acids 431 to 452 (22 residues), see Phobius details amino acids 470 to 495 (26 residues), see Phobius details amino acids 502 to 520 (19 residues), see Phobius details TIGR03409: urea ABC transporter, permease protein UrtB" amino acids 243 to 533 (291 residues), 440.7 bits, see alignment E=1.6e-136 PF02653: BPD_transp_2" amino acids 245 to 519 (275 residues), 167.4 bits, see alignment E=1.9e-53

Best Hits

KEGG orthology group: K01997, branched-chain amino acid transport system permease protein (inferred from 100% identity to sme:SM_b20604)

Predicted SEED Role

"Urea ABC transporter, permease protein UrtB" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92TJ6 at UniProt or InterPro

Protein Sequence (537 amino acids)

>SM_b20604 branched-chain amino acid ABC transporter permease (Sinorhizobium meliloti 1021)
MYRIIPTVLAALFLFVAMAPGLRAEEGLRDLVNALGEAKLSEMDEHIAALAKTGKPEVVA
ILEALGEGELYARKADGQVLLTKESGSNLTLTDPISGDSAGEAPKAALSKIRVNNSVRRA
VRTALGSLTLLSPDRNQRLRAAQSVLQSPDADALGVIENALAAEKDGAVRAVLEQARATM
LLLSDRPVEEKKEAVRLLEENGGREALPILSAALGSADESLKPDIEAALASIEQAQAFWN
AGQNIWYGLSLGSVLLLAAIGLAITFGVMGIINMAHGEMVMLGAYTTFLVQDVVRTSFPH
LFEWSLAIALPLAFLVTGAVGLALERGVIRFLYGRPLETLLATWGISLILQQTVRTIFGP
TNREVGNPSWMSGAFELGGLAITWNRLWIIVFALAVFAALLFLLKKTPMGLQMRAVTQNR
RMASSMGIRTPWVDALTFALGSGIAGIAGVALSQIDNVSPNLGQGYIIDSFMVVVFGGVG
NLWGTLVGAFSLGILNKFLEPYAGAVLGKILVLVLIILFIQKRPRGLFALKGRAVEA